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Down syndrome

or Down's syndrome

noun

, Pathology.
  1. a genetic disorder, associated with the presence of an extra chromosome 21, characterized by mild to severe mental impairment, weak muscle tone, shorter stature, and a flattened facial profile.


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Sensitive Note

Down syndrome (or Down's syndrome ) has replaced earlier terms, such as mongolism to refer to the disease and Mongoloid or Mongol to refer to the affected person, all of which are now considered offensive.
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Word History and Origins

Origin of Down syndrome1

First recorded in 1960–65; after John L. H. Down (1828–96), British physician
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Example Sentences

Advanced maternal age dramatically increases the risk of maternal mortality as well as birth defects like Down Syndrome.

Jolly somehow finds the time to also manage a restaurant and help kids who have Autism and Down syndrome ride horses.

In 1975, Sesame Street became the first children's program to feature someone with Down Syndrome.

Saylor, a 26-year-old man with Down syndrome, tried to re-watch a movie in a theater without buying another ticket.

Richard Dawkins recently tweeted that knowingly birthing a baby with Down syndrome is immoral.

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